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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCG2 All Species: 24.24
Human Site: T332 Identified Species: 48.48
UniProt: P16885 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P16885 NP_002652.2 1265 147870 T332 S S H N T Y L T G D Q L R S E
Chimpanzee Pan troglodytes XP_001147944 1265 147906 T332 S S H N T Y L T G D Q L R S E
Rhesus Macaque Macaca mulatta XP_001111677 1265 147898 T332 S S H N T Y L T G D Q L R S E
Dog Lupus familis XP_546812 1252 146274 T332 S S H N T Y L T G D Q L R S E
Cat Felis silvestris
Mouse Mus musculus Q8CIH5 1265 147573 T332 S S H N T Y L T G D Q L R S E
Rat Rattus norvegicus P24135 1265 147716 T332 S S H N T Y L T G D Q L R S E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508105 991 115582 S133 V Q G S A F D S G L G I S L R
Chicken Gallus gallus Q2VRL0 637 72514
Frog Xenopus laevis Q32NH8 758 87399
Zebra Danio Brachydanio rerio A5D6R3 784 89362
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_624101 1134 132613 A276 S C Q A Y V R A L R T G C R C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784329 940 107748 Q82 F G D T L L T Q P I D R D A A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 98 94.4 N.A. 94.1 94.7 N.A. 62.7 20.7 22.1 21.2 N.A. N.A. 40.9 N.A. 32.9
Protein Similarity: 100 99.9 99.2 97 N.A. 97.1 97.3 N.A. 67.8 33.2 37.5 34.9 N.A. N.A. 59.1 N.A. 49
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 6.6 0 0 0 N.A. N.A. 6.6 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 33.3 0 0 0 N.A. N.A. 6.6 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 9 9 0 0 9 0 0 0 0 0 9 9 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 9 0 9 % C
% Asp: 0 0 9 0 0 0 9 0 0 50 9 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 50 % E
% Phe: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 9 9 0 0 0 0 0 59 0 9 9 0 0 0 % G
% His: 0 0 50 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 9 50 0 9 9 0 50 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 50 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % P
% Gln: 0 9 9 0 0 0 0 9 0 0 50 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 9 0 0 9 0 9 50 9 9 % R
% Ser: 59 50 0 9 0 0 0 9 0 0 0 0 9 50 0 % S
% Thr: 0 0 0 9 50 0 9 50 0 0 9 0 0 0 0 % T
% Val: 9 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 50 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _